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EHS Center Membership
The EHS Center currently has
members comprised of scientists and physician scientists from both
the Wayne State University and University of Michigan campuses.
The following are the
Mission Statements of the Research Programs:
Gene Regulation and
Genetics (GRG) Research Program: To enhance the cooperation and
collaboration of Center investigators and others with research
interests directed toward understanding the interaction of genes and
the environment. Genetic elements and polymorphisms affecting
expression and/or function of enzymes metabolizing xenobiotics or
macromolecules modified by environmental agents are the foci of the
research programs.
Cell Signaling and
Function (CSF) Research Program: To encourage and facilitate the
interaction and collaboration of Center scientists who have
interests in understanding the mediators, modulators and mechanisms
of cell signaling in normal, neoplastic, and toxicant-perturbed
cells and tissues and relating signaling processes to cellular
function.
Early Events and
Environmental Factors in Proliferative Breast Disease and Cancer
Research Program:
To facilitate interactions among a broad based core of
scientists to examine the effects of environmental factors
implicated in breast cancer using a unique panel of cells derived
from a woman with fibrocystic disease. An additional interest is
prevention of the environmental factor-mediated response using
inhibitors of the proteasome and specific inhibitors of
tumor-stromal interactions.
Environmental
Pediatrics Research Program: To enhance collaboration of Center
investigators studying the genetic basis of childhood diseases
including cancer and the role of environmental exposures.
Community Outreach and
Education Core (COEC):
- To translate research
information into knowledge applied to public health;
- To focus public and
community outreach education initiatives on reducing
environmental disease risk and/or hazard exposure;
- To develop the
direction of the COEC in parallel with the research strengths of
the Center.
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